Recurrent pregnancy loss (RPL) is a condition where a woman experiences two or more consecutive miscarriages. These losses can occur at any stage of pregnancy, including the early first trimester, second trimester, or, in rare cases, the third trimester. However, RPL is typically defined as miscarriages occurring before 24 weeks of gestation.
Causes of Recurrent Pregnancy Loss
There are several potential causes of RPL, which may vary from case to case:
- Uterine Abnormalities: Structural issues with the uterus, such as uterine septum or fibroids, can increase the risk of pregnancy loss.
- Infections: Certain infections can impact fetal development, leading to miscarriage.
- Thrombophilia: Blood clotting disorders, which can reduce blood flow to the placenta, are another common cause.
- Genetic Factors: Chromosomal abnormalities in either parent can result in repeated miscarriages.
Role of Genetic Factors in RPL
Genetic issues contribute to a significant percentage of RPL cases. Chromosomal abnormalities, such as translocations or aneuploidies, may prevent the embryo from developing normally. Genetic counselling and investigations play a critical role in identifying these issues and helping couples understand their reproductive risks.
Additionally, genetic testing may provide insights into neurodevelopmental conditions or other potential health concerns that could affect future pregnancies.
Importance of Genetic Counselling for RPL
Genetic counselling is essential for couples experiencing RPL, as it:
- Identifies genetic causes of miscarriages.
- Provides clarity and emotional support to affected couples.
- Guides them on treatment options or preventative measures, such as preimplantation genetic testing (PGT) during in-vitro fertilization (IVF).
Seeking Expert Support
If you are facing recurrent pregnancy loss or have concerns about your pregnancy, the Institute of Fetal Medicine, Kolkata, offers expert care, genetic counselling, and comprehensive support tailored to your needs.
Contact us:
📞 9830047676 / 9748480005 / 9831788538